Nanoparticle screening chip collectors
A method and a device to rapidly determine the key properties of nanoparticles (NMs). Surface hydrophobicity governs cellular uptake, toxicity, immune response, hemolysis and protein adsorption — and it plays a decisive role in the development of nanoparticle-based vaccine adjuvants.
Today no single method measures both surface properties and size at once: size is determined by optical or imaging techniques, surface chemistry requires XPS or ToF-SIMS. Accurate, but slow and specialist-bound — while nanomaterials are now everywhere.
Our chip solves the problem in a single pass. The surface is divided into areas with specific properties — hydrophobicity and charge — and each hosts sub-zones with micro-holes or micro-grooves at calibrated sizes. Nanoparticles separate simultaneously by surface chemistry and by size. The properties of some areas are modified through cold plasma treatment (not dry chemistry), to capture specific nanomaterials.
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One-step nanoparticle characterization
Simultaneous evaluation of surface properties and nanoparticle size distribution in a single workflow.
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Rapid alternative to multi-technique analysis
Replaces the need for XPS, ToF-SIMS, optical microscopy and imaging-based size distribution methods.
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OECD Test Guideline 126 compliant
Supports standardized determination of nanomaterial hydrophobicity according to internationally recognized protocols.
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JRC-licensed innovation
Developed and validated in collaboration with the European Commission Joint Research Centre.
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Bridges a critical analytical gap
First approach enabling combined surface chemistry + size distribution analysis in a streamlined process.
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High-throughput ready
Fast screening for R&D, pharma, diagnostics, nanomedicine and Quality control materials